NEJM· Kasiani C. MyersCincinnati Children’s Hospital Medical Center, CincinnatiJean DonadieuSorbonne Université–Hôpital Armand-Trousseau, Assistance Publique–Hôpitaux de Paris, ParisBenjamin GoldbergManon DelafoyBoston Children’s Hospital, BostonCornelia ZeidlerSabine Mellor-HeinekeUniversity of Tubingen, Tubingen, GermanyYang WanXiaofan ZhuInstitute of Hematology and Blood Diseases Hospital, Tianjin, ChinaSimone CesaroMarco CipolliAzienda Ospedaliera Universitaria Integrata Verona, Verona, ItalyKenichiro WatanabeShizuoka Children’s Hospital, Shizuoka, JapanLucy C. FoxMonash University, Melbourne, VIC, AustraliaCaroline RuttenTaco W. KuijpersAmsterdam University Medical Center, AmsterdamAntonis KattamisPolyxeni DelaportaNational and Kapodistrian University of Athens, AthensUlla Wartiovaara-KauttoOuti KilpivaaraHelsinki University Hospital Comprehensive Cancer Center, HelsinkiAlison A. BertuchCandelaria O’FarrellBaylor College of Medicine, HoustonMelanie CotterEoghan DunleaChildren’s Health Ireland, DublinChristopher R. ReillyDana–Farber Cancer Institute, BostonAlan J. WarrenUniversity of Cambridge, Cambridge, United KingdomAmy GeddisSeattle Children’s Hospital, SeattleEdie WellerAkiko Shimamurafor the International SDS Research Consortium*Boston Children’s Hospital, Boston·· 13 天前AI 评分6
Shwachman–Diamond 综合征的累积血液学发病与结局
Cumulative Hematologic Morbidity and Outcomes in Shwachman–Diamond Syndrome
AI 导读
一项发表于 NEJM 的研究显示，Shwachman–Diamond 综合征（SDS）患者随年龄增长累积发生骨髓衰竭、骨髓增生异常综合征（MDS）和急性髓系白血病（AML）的风险显著升高。该研究基于长期随访队列，量化了不同年龄段的血液学事件累积发生率，并提示需对 SDS 患者进行持续血液学监测。
来源：NEJM · nejm.org