NEJM· Yves Dauvilliers Emmanuel Mignot Jakub Antczak Isabelle Arnulf Lucie Barateau Erik Buntinx Bruce Corser Alex Iranzo Ramin Khatami Gert Jan Lammers Katharina Lederer Kristian Bernhard Nilsen Fabio Pizza Markus H. Schmidt Sheila Sivam Oliver Sum-Ping Mitsutaka Taniguchi Shuqin Zhan Anson Abraham Alice Cai Yeting Du Mark R. Etherton Helene Faessel Samuel Hsiao Harisha Kadali Elena Koundourakis Melissa Naylor Rachel Neuwirth Tina Olsson Raquel Rogers Sarah Sheikh Shinichiro Tanaka Philipp von Rosenstiel Christian von Hehn Yaming Hang Baiyun Yao Rafael del Rio Villegas and Giuseppe Plazzi·· 27 天前AI 评分31
Oveporexton 治疗 1 型发作性睡病：两项 3 期临床试验结果
Oveporexton for Narcolepsy Type 1 — Results from Two Phase 3 Trials
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Oveporexton 在两项 3 期临床试验中显著改善 1 型发作性睡病患者的日间过度嗜睡与猝倒发作。试验达到主要终点，Oveporexton 组较安慰剂组在 Epworth 嗜睡量表和每周猝倒次数上均显示统计学显著改善，安全性数据与既往研究一致。研究发表于 NEJM 2026 年 9 月刊。
来源：NEJM · nejm.org